Folate that is consumed in food is in its inactive form, and it was proven that only active form of folate 5MTHF has influence on lowering homocysteine level. With a large number of people, folate cannot transform into its active form due to lack of certain enzymes, therefore it is more effective to take folate in its active form as 5MTHF. This is the reason why all the patients that have problems with heart and blood vessels are recommended additional supplementation with active form of folate. Among other things, CARDIOvitamin® is unique for its active form of folate 5MTHF.